This page contains the peer-reviewed publications by the MSRC reseachers since 2012.

Abel Baerga Ortíz, Ph.D.

    1. Gómez-Moreno R, Robledo IE, Baerga-Ortiz A. Direct Detection and Quantification of Bacterial Genes Associated with Inflammation in DNA Isolated from Stool. Adv Microbiol. 2014 Nov;4(15):1065-1075. PubMed PMID: 25635239;PubMed Central PMCID: PMC4307837.
    2. Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. RSC Adv. 2014 Oct 15;4(94):52357-52365. PubMed PMID: 25598969; PubMed Central PMCID: PMC4295792.
    3. Oyola-Robles D, Rullán-Lind C, Carballeira NM, Baerga-Ortiz A. Expression of dehydratase domains from a polyunsaturated fatty acid synthase increases the production of fatty acids in Escherichia coli. Enzyme Microb Technol. 2014 Feb 5;55:133-9. doi: 10.1016/j.enzmictec.2013.10.010. Epub 2013 Nov 8. PubMed PMID: 24411456; PubMed Central PMCID: PMC3894691.
    4. Oyola-Robles D, Gay DC, Trujillo U, Sánchez-Parés JM, Bermúdez ML, Rivera-Díaz M, Carballeira NM, Baerga-Ortiz A. Identification of novel protein domains required for the expression of an active dehydratase fragment from a polyunsaturated fatty acid synthase. Protein Sci. 2013 Jul;22(7):954-63. doi:10.1002/pro.2278. Epub 2013 Jun 6. PubMed PMID: 23696301; PubMed Central PMCID:PMC3719089.
    5. Trujillo U, Vázquez-Rosa E, Oyola-Robles D, Stagg LJ, Vassallo DA, Vega IE, Arold ST, Baerga-Ortiz A. Solution structure of the tandem acyl carrier protein domains from a polyunsaturated fatty acid synthase reveals beads-on-a-string configuration. PLoS One. 2013;8(2):e57859. doi: 10.1371/journal.pone.0057859.Epub 2013 Feb 28. PubMed PMID: 23469090; PubMed Central PMCID: PMC3585217.
    6. Rodríguez-Guilbe M, Oyola-Robles D, Schreiter ER, Baerga-Ortiz A. Structure, activity, and substrate selectivity of the Orf6 thioesterase from Photobacterium profundum. J Biol Chem. 2013 Apr 12;288(15):10841-8. doi:10.1074/jbc.M112.446765. Epub 2013 Feb 21. PubMed PMID: 23430744; PubMed Central PMCID: PMC3624464.

Abimael Rodriguez, Ph.D

  1. Avilés E, Prudhomme J, Le Roch KG, Rodríguez AD. Structures, semisyntheses, and absolute configurations of the antiplasmodial α-substituted β-lactam monamphilectines B and C from the sponge Svenzea flava. Tetrahedron. 2015 Jan 21;71(3):487-494. PubMed PMID: 26494928; PubMed Central PMCID: PMC4610402.
  2. Avilés E, Prudhomme J, Le Roch KG, Franzblau SG, Chandrasena K, Mayer AM, Rodríguez AD. Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5339-43. doi: 10.1016/j.bmcl.2015.09.033. Epub 2015 Sep 15. PubMed PMID: 26421992.
  3. Avilés E, Rodríguez AD. Euryjanicins E-G, poly-phenylalanine and poly-proline cyclic heptapeptides from the Caribbean sponge Prosuberites laughlini. Tetrahedron. 2013 Dec 23;69(51):10797-10804. Epub 2013 Nov 5. PubMed PMID: 26491207; PubMed Central PMCID: PMC4610400.
  4. Jiménez-Romero C, Mayer AM, Rodríguez AD. Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity. Bioorg Med Chem Lett. 2014 Jan 1;24(1):344-8. doi: 10.1016/j.bmcl.2013.11.008. Epub 2013 Nov 14. PubMed PMID:24279991; PubMed Central PMCID: PMC4249741.
  5. Avilés E, Rodríguez AD, Vicente J. Two rare-class tricyclic diterpenes with antitubercular activity from the Caribbean sponge Svenzea flava. Application of vibrational circular dichroism spectroscopy for determining absolute configuration. J Org Chem. 2013 Nov 15;78(22):11294-301. doi: 10.1021/jo401846m. Epub 2013 Nov 5. PubMed PMID: 24138557; PubMed Central PMCID: PMC4610370.
  6. Li J, Cisar JS, Zhou CY, Vera B, Williams H, Rodríguez AD, Cravatt BF, Romo D. Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate. Nat Chem. 2013 Jun;5(6):510-7. doi: 10.1038/nchem.1653. Epub 2013 May 19. Erratum in: Nat Chem. 2013 Jul;5(7):634. PubMed PMID: 23695633; PubMed Central PMCID: PMC4041531.
  7. González K, Nieves K, Rodríguez AD. 3β-Chloro-N-methoxy-N-methyl-cholest-5-ene-24-carboxamide. Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3471. doi: 10.1107/S160053681204679X.  Epub 2012 Nov 28. PubMed PMID: 23476280; PubMed Central PMCID: PMC3589044.
  8. Rodríguez-Escudero I, Marrero J, Rodríguez AD. Kallolide A acetate pyrazoline. Acta Crystallogr Sect E Struct Rep Online. 2012 Jan;68(Pt 1):o41-2. doi: 10.1107/S1600536811051890. Epub 2011 Dec 7. PubMed PMID: 22259545; PubMed Central PMCID: PMC3254402.
  9. Mayer AM, Avilés E, Rodríguez AD. Marine sponge Hymeniacidon sp. amphilectane metabolites potently inhibit rat brain microglia thromboxane B2 generation. Bioorg Med Chem. 2012 Jan 1;20(1):279-82. doi: 10.1016/j.bmc.2011.10.086. Epub 2011 Nov 9. PubMed PMID: 22153874; PubMed Central PMCID: PMC3272584.

Alexis García, DVM

  1. Esmail MY, Qi P, Burds A, Fox JG, García A. Efficiencies of generating JM8A3.N1 ES-cell chimeric mice using embryos from superovulated albino C57BL/6 mice and superovulated and non-superovulated BALB/c mice. Accepted for publication (J Am Assoc Lab Anim Sci).
  2. Swennes AG, Sheh A, Parry NM, Muthupalani S, Lertpiriyapong K, García A, Fox JG. Helicobacter hepaticus infection promotes hepatitis and preneoplastic foci in farsenoid X receptor (FXR) deficient mice. PLoS One. 2015 Sep 3;9(9):e106764.
  3. Borjeson TM, Pang J, Fox JG, García A. Administration of lutenizing hormone releasing hormone agonist for synchronization of estrus and generation of pseudopregnancy for embryo transfer in rats. 2014 May;53(3):232-237.
  4. Woods SE, Qi P, Rosalia E, Chavarria T, Discua A, Mkandawire J, Fox JG, García A. Laser-assisted in vitro fertilization facilitates fertilization of vitrified-warmed C57BL/6 mouse oocytes with fresh and frozen-thawed spermatozoa, producing live pups. PLoS One, 2014 Mar 11;9(3):e91892.
  5. García A, Feng Y, Parry NM, McCabe A, Mobley MW, Lertpiriyapong K, Whary MT, Fox JG. Helicobacter pylori infection does not promote hepatocellular cancer in a transgenic mouse model of hepatitis C virus pathogenesis. Gut Microbes. 2013 Nov-Dec;4(6):577-590.
  6. Swennes AG, Buckley EM, Parry NM, Madden CM, García A, Morgan PB, Astrofsky KM, Fox JG. Enzootic enteropathogenic Escherichia coli infection in laboratory rabbits. J Clin Microbiol. 2012 Jul;50(7):2353-2358.

Brad Weiner, Ph.D.

  1. Rojas-Pérez A, Diaz-Diestra D, Frias-Flores CB, Beltran-Huarac J, Das KC, Weiner BR, Morell G, Díaz-Vázquez LM. Catalytic effect of ultrananocrystalline Fe3O4 on algal bio-crude production via HTL process. Nanoscale. 2015 Nov 14;7(42):17664-71. doi: 10.1039/c5nr04404a. Epub 2015 Oct 14. PubMed PMID: 26465090.
  2. Palomino J, Varshney D, Resto O, Weiner BR, Morell G. Ultrananocrystalline diamond-decorated silicon nanowire field emitters. ACS Appl Mater Interfaces. 2014 Aug 27;6(16):13815-22. doi: 10.1021/am503221t. Epub 2014 Jul 28. PubMed PMID: 25046006.
  3. Beltran-Huarac J, Resto O, Carpena-Nuñez J, Jadwisienczak WM, Fonseca LF, Weiner BR, Morell G. Single-crystal γ-MnS nanowires conformally coated with carbon. ACS Appl Mater Interfaces. 2014 Jan 22;6(2):1180-6. doi: 10.1021/am404746k. Epub 2014 Jan 10. PubMed PMID: 24392737.
  4. Varshney D, Ahmadi M, Guinel MJ, Weiner BR, Morell G. Single-step route to diamond-nanotube composite. Nanoscale Res Lett. 2012 Sep 27;7(1):535. doi: 10.1186/1556-276X-7-535. PubMed PMID: 23013660; PubMed Central PMCID: PMC3519742.

Carlos Cabrera, Ph.D.

  1. Corchado-García J, Betancourt LE, Vélez CA, Senanayake SD, Stacchiola D, Sasaki K, Guinel MJ, Zhou Y, Cheung CL, Cabrera CR. Cerium oxide as a promoter for the electro-oxidation reaction of ethanol: in situ XAFS characterization of the Pt nanoparticles supported on CeO(2) nanoparticles and nanorods. Phys Chem Chem Phys. 2015 Nov 18. [Epub ahead of print] PubMed PMID: 26580293.
  2. Hernández-Cancel G, Suazo-Dávila D, Ojeda-Cruzado AJ, García-Torres D, Cabrera CR, Griebenow K. Graphene oxide as a protein matrix: influence on protein biophysical properties. J Nanobiotechnology. 2015 Oct 19;13(1):70. doi: 10.1186/s12951-015-0134-0. PubMed PMID: 26482026; PubMed Central PMCID:PMC4617716.
  3. Lin YG, Colón-García JE, Cabrera CR, Quiñones E. Implementation of Various Modalities of the Optical-Optical Double Resonance Techniques To Simplify the Interpretation of the Spectra of Highly Excited States of Nitric Oxide. J Phys Chem A. 2015 Aug 6;119(31):8476-87. doi: 10.1021/acs.jpca.5b04980. Epub 2015 Jul 29. PubMed PMID: 26166549.
  4. Feliciano-Ramos I, Casañas-Montes B, García-Maldonado MM, Menéndez CL, Mayol AR, Díaz-Vázquez LM, Cabrera CR. Assembly of a Cost-Effective Anode Using Palladium Nanoparticles for Alkaline Fuel Cell Applications. J Chem Educ. 2015 Feb 10;92(2):360-363. PubMed PMID: 25691801; PubMed Central PMCID: PMC4325606.
  5. Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. RSC Adv. 2014 Oct 15;4(94):52357-52365. PubMed PMID: 25598969; PubMed Central PMCID: PMC4295792.
  6. Piñero F, Marciano S, Anders M, Orozco F, Zerega A, Cabrera CR, Baña MT, Gil O, Andriani O, de Santibañes E, McCormack L, Gadano A, Silva M. Screening for liver cancer during transplant waiting list: a multicenter study from South America. Eur J Gastroenterol Hepatol. 2015 Mar;27(3):355-60. doi: 10.1097/MEG.0000000000000272. PubMed PMID: 25563142.
  7. Martínez-Rodríguez RA, Vidal-Iglesias FJ, Solla-Gullón J, Cabrera CR, Feliu JM. Synthesis and electrocatalytic properties of H2SO4 -induced (100) Pt nanoparticles prepared in water-in-oil microemulsion. Chemphyschem. 2014 Jul 21;15(10):1997-2001. doi: 10.1002/cphc.201400056. Epub 2014 Mar 19. PubMed PMID: 24648299.
  8. Martínez-Rodríguez RA, Vidal-Iglesias FJ, Solla-Gullón J, Cabrera CR, Feliu JM. Synthesis of Pt Nanoparticles in Water-in-Oil Microemulsion: Effect of HCl on Their Surface Structure. J Am Chem Soc. 2014 Jan 29;136(4):1280-3. doi:10.1021/ja411939d. Epub 2014 Jan 21. PubMed PMID: 24422507.
  9. Cunci L, Velez CA, Perez I, Suleiman A, Larios E, José-Yacamán M, Watkins JJ, Cabrera CR. Platinum electrodeposition at unsupported electrochemically reduced nanographene oxide for enhanced ammonia oxidation. ACS Appl Mater Interfaces. 2014 Feb 12;6(3):2137-45. doi: 10.1021/am4052552. Epub 2014 Jan 17. PubMed PMID: 24417177; PubMed Central PMCID: PMC3985924.
  10. Arroyo-Ramírez L, Montano-Serrano R, Luna-Pineda T, Román FR, Raptis RG, Cabrera CR. Synthesis and characterization of palladium and palladium-cobalt nanoparticles on Vulcan XC-72R for the oxygen reduction reaction. ACS Appl Mater 2013 Nov 27;5(22):11603-12. doi: 10.1021/am402932h. Epub 2013 Nov 5. PubMed PMID: 24102312.
  11. Li Y, Zhou Z, Cabrera CR, Chen Z. Preserving the edge magnetism of zigzag graphene nanoribbons by ethylene termination: insight by Clar’s rule. Sci Rep. 2013;3:2030. doi: 10.1038/srep02030. PubMed PMID: 23778381; PubMed Central PMCID: PMC3686159.
  12. Santiago D, Rodríguez-Calero GG, Palkar A, Barraza-Jimenez D, Galvan DH, Casillas G, Mayoral A, Jose-Yacamán M, Echegoyen L, Cabrera CR. Platinum electrodeposition on unsupported carbon nano-onions. Langmuir. 2012 Dec 11;28(49):17202-10. doi: 10.1021/la3031396. Epub 2012 Nov 26. PubMed PMID: 23145813.
  13. Li Y, Wu D, Zhou Z, Cabrera CR, Chen Z. Enhanced Li Adsorption and Diffusion on MoS2 Zigzag Nanoribbons by Edge Effects: A Computational Study. J Phys Chem Lett. 2012 Aug 16;3(16):2221-7. doi: 10.1021/jz300792n. Epub 2012 Aug 2. PubMed PMID: 26295774.
  14. Arroyo-Ramírez L, Rodríguez D, Otaño W, Cabrera CR. Palladium nanoshell catalysts synthesis on highly ordered pyrolytic graphite for oxygen reduction reaction. ACS Appl Mater Interfaces. 2012 Apr;4(4):2018-24. doi: 10.1021/am201860r. Epub 2012 Mar 20. PubMed PMID: 22360356.
  15. La-Torre-Riveros L, Guzman-Blas R, Méndez-Torres AE, Prelas M, Tryk DA, Cabrera CR. Diamond nanoparticles as a support for Pt and PtRu catalysts for direct methanol fuel cells. ACS Appl Mater Interfaces. 2012 Feb;4(2):1134-47. doi: 10.1021/am2018628. Epub 2012 Feb 9. PubMed PMID: 22270177.
  16. Jesus EC, Santiago D, Casillas G, Mayoral A, Magen C, José-Yacaman M, Li J, Cabrera CR. Platinum Electrodeposition on Unsupported Single Wall Carbon Nanotubes and Its Application as Methane Sensing Material. J Electrochem Soc. 2012;160(2):H98-H104. PubMed PMID: 24991061; PubMed Central PMCID: PMC4074597.
  17. Nicolau E, Méndez J, Fonseca JJ, Griebenow K, Cabrera CR. Bioelectrochemistry of non-covalent immobilized alcohol dehydrogenase on oxidized diamond nanoparticles. Bioelectrochemistry. 2012 Jun;85:1-6. doi: 10.1016/j.bioelechem.2011.11.002. Epub 2011 Nov 20. PubMed PMID: 22154812.

Carlos Gonzalez, Ph.D.

  1. Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. RSC Adv. 2014 Oct 15;4(94):52357-52365. PubMed PMID: 25598969; PubMed Central PMCID: PMC4295792.
  2. González-Feliciano JA, Hernández-Pérez M, Estrella LA, Colón-López DD, López A, Martínez M, Maurás-Rivera KR, Lasalde C, Martínez D, Araujo-Pérez F, González CI. The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells. PLoS One. 2014 Mar 21;9(3):e92457. doi: 10.1371/journal.pone.0092457. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e106296. PubMed PMID: 24658545; PubMed Central PMCID: PMC3962401.
  3. Lasalde C, Rivera AV, León AJ, González-Feliciano JA, Estrella LA, Rodríguez-Cruz EN, Correa ME, Cajigas IJ, Bracho DP, Vega IE, Wilkinson MF, González CI. Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. Nucleic Acids Res. 2014 Feb;42(3):1916-29. doi: 10.1093/nar/gkt1049. Epub 2013 Nov 5. PubMed PMID: 24198248; PubMed Central PMCID: PMC3919615.
  4. Castillo B, Bromberg L, López X, Badillo V, González Feliciano JA, González CI, Hatton TA, Barletta G. Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles. J Drug Deliv. 2012;2012:218940. doi: 10.1155/2012/218940. Epub 2012 Aug 30. PubMed PMID: 22970377; PubMed Central PMCID: PMC3437298.

Carmen Cadilla, Ph.D.

    1. Claudio-Campos K, Orengo-Mercado C, Renta JY, Peguero M, García R, Hernández G, Corey S, Cadilla CL, Duconge J. Pharmacogenetics of healthy volunteers in Puerto Rico. Drug Metabol Personal Ther. 2015 Dec 1;30(4):239-49. doi: 10.1515/dmpt-2015-0021. PubMed PMID: 26501165.
    2. Díaz-Ayala R, Moya-Rodríguez A, Pietri R, Cadilla CL, López-Garriga J. Molecular Cloning and Characterization of a (Lys)(6)-Tagged Sulfide-Reactive Hemoglobin I from Lucina pectinata. Mol Biotechnol. 2015 Oct 19. [Epub ahead of print] PubMed PMID: 26482241.
    3. Rosti RO, Uyguner ZO, Nazarenko I, Bekerecioglu M, Cadilla CL, Ozgur H, Lee BH, Aggarwal AK, Pehlivan S, Desnick RJ. Setleis syndrome: clinical, molecular and structural studies of the first TWIST2 missense mutation. Clin Genet. 2015 Nov;88(5):489-93. doi: 10.1111/cge.12539. Epub 2014 Dec 11. PubMed PMID: 25410422.
    4. Valentín II, Rivera G, Nieves-Plaza M, Cruz I, Renta JY, Cadilla CL, Feliu JF, Seip RL, Ruaño G, Duconge J. Pharmacogenetic association study of warfarin safety endpoints in Puerto Ricans. P R Health Sci J. 2014 Sep;33(3):97-104. PubMed PMID:25244877; PubMed Central PMCID: PMC4196861.
    5. Jardón J, Izquierdo NJ, Renta JY, García-Rodríguez O, Cadilla CL. Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3). Ophthalmic Genet. 2015 Aug 21:1-6. [Epub ahead of print] PubMed PMID: 24766090; PubMed Central PMCID: PMC4232478.
    6. Duconge J, Cadilla CL. CYP2D6’s functional status associated with the length of hospitalization stay in psychiatric patients: a twist in the tale or evidence that matters? Biomark Med. 2013 Dec;7(6):913-4. doi: 10.2217/bmm.13.109. PubMed PMID: 24266824; PubMed Central PMCID: PMC4109677.
    7. Orengo-Mercado C, Nieves B, López L, Vallés-Ortiz N, Renta JY, Santiago-Borrero PJ, Cadilla CL, Duconge J. Frequencies of Functional Polymorphisms in Three Pharmacokinetic Genes of Clinical Interest within the Admixed Puerto Rican Population. J Pharmacogenomics Pharmacoproteomics. 2013 Mar 27;4(113). pii: 1000113. PubMed PMID: 24040574; PubMed Central PMCID: PMC3769800.
    8. Ramos AS, Seip RL, Rivera-Miranda G, Felici-Giovanini ME, Garcia-Berdecia R, Alejandro-Cowan Y, Kocherla M, Cruz I, Feliu JF, Cadilla CL, Renta JY, Gorowski K, Vergara C, Ruaño G, Duconge J. Development of a pharmacogenetic-guided warfarin dosing algorithm for Puerto Rican patients. Pharmacogenomics. 2012 Dec;13(16):1937-50. doi: 10.2217/pgs.12.171. PubMed PMID: 23215886; PubMed Central PMCID: PMC3538136.

Dalice Piñero, Ph.D.

  1. Famengo; Piñero; O. Jeannin; T. Guizouarn; M. Fourmigué, ‘’Paramagnetic dithiolene complexes as metallo-ligands: ether/thioether coordination’’ Dalton Trans., 2012, 41, 1441–1443.
  2. -R. Jeon; S. Calancea;A. Panja; D. Piñero; P. Dechambenoit; C. Coulon; A. Wattiaux; P. Rosa; C. Mathonière; R. Clérac, “Spin crossover or intra-molecular electron transfer in a cyanido-bridged Fe/Co dinuclear dumbbell: a matter of state”, Chem. Sci., 2013, 4, 2463-2470.

Eduardo Nicolao, Ph.D.

  1. Nicolau E, Méndez J, Fonseca JJ, Griebenow K, Cabrera CR. Bioelectrochemistry of non-covalent immobilized alcohol dehydrogenase on oxidized diamond nanoparticles. Bioelectrochemistry. 2012 Jun;85:1-6. doi: 10.1016/j.bioelechem.2011.11.002. Epub 2011 Nov 20. PubMed PMID: 22154812.

Gerardo Morell, Ph.D.

  1. Rojas-Pérez A, Diaz-Diestra D, Frias-Flores CB, Beltran-Huarac J, Das KC, Weiner BR, Morell G, Díaz-Vázquez LM. Catalytic effect of ultrananocrystalline Fe3O4 on algal bio-crude production via HTL process. Nanoscale. 2015 Nov 14;7(42):17664-71. doi: 10.1039/c5nr04404a. Epub 2015 Oct 14. PubMed PMID: 26465090.
  2. Feng P, Sajjad M, Li EY, Zhang H, Chu J, Aldalbahi A, Morell G. Fringe structures and tunable bandgap width of 2D boron nitride nanosheets. Beilstein J Nanotechnol. 2014 Jul 31;5:1186-92. doi: 10.3762/bjnano.5.130. eCollection 2014. PubMed PMID: 25161852; PubMed Central PMCID: PMC4142973.
  3. Palomino J, Varshney D, Resto O, Weiner BR, Morell G. Ultrananocrystalline diamond-decorated silicon nanowire field emitters. ACS Appl Mater Interfaces. 2014 Aug 27;6(16):13815-22. doi: 10.1021/am503221t. Epub 2014 Jul 28. PubMed PMID: 25046006.
  4. Beltran-Huarac J, Resto O, Carpena-Nuñez J, Jadwisienczak WM, Fonseca LF, Weiner BR, Morell G. Single-crystal γ-MnS nanowires conformally coated with carbon. ACS Appl Mater Interfaces. 2014 Jan 22;6(2):1180-6. doi: 10.1021/am404746k. Epub 2014 Jan 10. PubMed PMID: 24392737.

José A. Lasalde Dominicci, Ph.D.

  1. Delgado-Vélez, M and Lasalde-Dominicci, JA. Inflamación periferal inducida por VIH: un problema sin resolver. Revista Puertorriqueña de Medicina y Salud Pública. (2016). Mar. Vol 54, 92-96.
  1. Delgado-Vélez, M., Baez-Pagan, C.A., Gerena, Y., Quesada, O., Santiago-Perez, L.I., Capo-Velez, C., Wojna, V., Melendez, L., Leon, R., Lasalde-Dominicci, J. The α7 nicotinic receptor is up-regulated in macrophages from HIV-seropositive women: Consequences to the cholinergic anti-inflammatory response. Clinical & Translational Immunology. (2015). Dec 11:4(12):e53 DOI:10.1038/cti.2015.31.
  2. Ramos FM, Delgado-Vélez M, Ortiz ÁL, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. Expression of CHRFAM7A and CHRNA7 in neuronal cells and postmortem brain of HIV-infected patients: considerations for HIV-associated neurocognitive disorder. J Neurovirol. 2015 Nov 13. [Epub ahead of print] PubMed PMID: 26567012.
  3. Melendez RI, Roman C, Capo-Velez CM, Lasalde-Dominicci JA. Decreased glial and synaptic glutamate uptake in the striatum of HIV-1 gp120 transgenic mice. J Neurovirol. 2015 Nov 13. [Epub ahead of print] PubMed PMID: 26567011.
  4. Padilla-Morales LF, Colón-Sáez JO, González-Nieves JE, Quesada-González O, Lasalde-Dominicci JA. Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology. Biochim Biophys Acta. 2016 Jan;1858(1):47-56. doi:10.1016/j.bbamem.2015.10.002. Epub 2015 Oct 8. PubMed PMID: 26454038.
  5. Oyola-Cintrón J, Caballero-Rivera D, Ballester L, Baéz-Pagán CA, Martínez HL, Vélez-Arroyo KP, Quesada O, Lasalde-Dominicci JA. Lateral Diffusion, Function, and Expression of the Slow Channel Congenital Myasthenia Syndrome αC418W Nicotinic Receptor Mutation with Changes in Lipid Raft Components. J Biol Chem.2015 Oct 30;290(44):26790-800. doi: 10.1074/jbc.M115.678573. Epub 2015 Sep 9. PubMed PMID: 26354438; PubMed Central PMCID: PMC4646332.
  6. Biaggi-Labiosa NM, Avilés-Pagán E, Caballero-Rivera D, Báez-Pagán CA, Lasalde-Dominicci JA. Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit. Neuropharmacology. 2015 Dec;99:273-84. doi:10.1016/j.neuropharm.2015.04.022. Epub 2015 May 6. PubMed PMID: 25957813; PubMed Central PMCID: PMC4636472.
  7. Báez-Pagán CA, Delgado-Vélez M, Lasalde-Dominicci JA. Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation. J Neuroimmune Pharmacol. 2015 Sep;10(3):468-76. doi: 10.1007/s11481-015-9601-5. Epub 2015 Apr 14. PubMed PMID: 25870122; PubMed Central PMCID: PMC4546521.
  8. Zhu H, Grajales-Reyes GE, Alicea-Vázquez V, Grajales-Reyes JG, Robinson K, Pytel P, Báez-Pagán CA, Lasalde-Dominicci JA, Gomez CM. Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome. Exp Neurol. 2015 Aug;270:88-94. doi: 10.1016/j.expneurol.2014.10.008. Epub 2014 Oct 23. PubMed PMID: 25448156; PubMed Central PMCID: PMC4430442.
  9. Grajales-Reyes GE, Báez-Pagán CA, Zhu H, Grajales-Reyes JG, Delgado-Vélez M, García-Beltrán WF, Luciano CA, Quesada O, Ramírez R, Gómez CM, Lasalde-Dominicci JA. Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions. Pharmacogenomics J. 2013 Aug;13(4):362-8. doi: 10.1038/tpj.2012.21. Epub 2012 Jun 12. PubMed PMID: 22688219; PubMed Central PMCID: PMC3972001.
  10. Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, Torres-Nunez DA, Otero-Cruz JD, Lasalde-Dominicci JA. Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin). 2012 Mar-Apr;6(2):111-23. doi: 10.4161/chan.19540. Epub 2012 Mar 1. PubMed PMID: 22622285; PubMed Central PMCID: PMC3396688.
  11. Salgado IK, Serrano M, García JO, Martínez NA, Maldonado HM, Báez-Pagán CA, Lasalde-Dominicci JA, Silva WI. SorLA in glia: shared subcellular distribution patterns with caveolin-1. Cell Mol Neurobiol. 2012 Apr;32(3):409-21. doi: 10.1007/s10571-011-9771-5. Epub 2011 Nov 30. PubMed PMID: 22127416; PubMed Central PMCID: PMC3753200.
  12. Ballester LY, Capó-Vélez CM, García-Beltrán WF, Ramos FM, Vázquez-Rosa E, Ríos R, Mercado JR, Meléndez RI, Lasalde-Dominicci JA. Up-regulation of the neuronal nicotinic receptor α7 by HIV glycoprotein 120: potential implications for HIV-associated neurocognitive disorder. J Biol Chem. 2012 Jan 27;287(5):3079-86. doi: 10.1074/jbc.M111.262543. Epub 2011 Nov 14. PubMed PMID:22084248; PubMed Central PMCID: PMC3270964.

José Rivera, Ph.D.

  1. Betancourt JE, Rivera JM. Tuning thermoresponsive supramolecular G-quadruplexes. Langmuir. 2015 Feb 24;31(7):2095-103. doi: 10.1021/la504446k. Epub 2015 Feb 10. PubMed PMID: 25641343.
  2. Rivera JM, Silva-Brenes D. A photoresponsive supramolecular G-quadruplex. Org Lett. 2013 May 17;15(10):2350-3. doi: 10.1021/ol400610x. Epub 2013 May 3. PubMed PMID: 23642252; PubMed Central PMCID: PMC3766467.
  3. Negrón LM, Meléndez-Contés Y, Rivera JM. Patchy supramolecules as versatile tools to probe hydrophobicity in nanoglobular systems. J Am Chem Soc. 2013 Mar 13;135(10):3815-7. doi: 10.1021/ja401373h. Epub 2013 Feb 27. PubMed PMID: 23432409; PubMed Central PMCID: PMC3646530.
  4. Rivera JM, Martín-Hidalgo M, Rivera-Ríos JC. An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin. Org Biomol Chem. 2012 Oct 7;10(37):7562-5. doi: 10.1039/c2ob25913c. PubMed PMID: 22895684; PubMed Central PMCID: PMC3646657.

Kai Griebenow, Ph.D.

  1. Hernández-Cancel G, Suazo-Dávila D, Ojeda-Cruzado AJ, García-Torres D, Cabrera CR, Griebenow K. Graphene oxide as a protein matrix: influence on protein biophysical properties. J Nanobiotechnology. 2015 Oct 19;13(1):70. doi:10.1186/s12951-015-0134-0. PubMed PMID: 26482026; PubMed Central PMCID: PMC4617716.
  2. Saxena M, Sharma RK, Ramirez-Paz J, Tinoco AD, Griebenow K. Purification and characterization of a cytochrome c with novel caspase-3 activation activity from the pathogenic fungus Rhizopus arrhizus. BMC Biochem. 2015 Sep 3;16:21. doi: 10.1186/s12858-015-0050-9. PubMed PMID: 26334686; PubMed Central PMCID: PMC4559206.
  3. Delgado Y, Morales-Cruz M, Figueroa CM, Hernández-Román J, Hernández G, Griebenow K. The cytotoxicity of BAMLET complexes is due to oleic acid and independent of the α-lactalbumin component. FEBS Open Bio. 2015 May 4;5:397-404. doi: 10.1016/j.fob.2015.04.010. eCollection 2015. PubMed PMID: 26101738; PubMed Central PMCID: PMC4430638.
  4. Hernández-Cancel G, Suazo-Dávila D, Medina-Guzmán J, Rosado-González M, Díaz-Vázquez LM, Griebenow K. Chemically glycosylation improves the stability of an amperometric horseradish peroxidase biosensor. Anal Chim Acta. 2015 Jan 7;854:129-39. doi: 10.1016/j.aca.2014.11.008. Epub 2014 Nov 7. PubMed PMID: 25479876; PubMed Central PMCID: PMC4292887.
  5. Pagán M, Suazo D, Del Toro N, Griebenow K. A comparative study of different protein immobilization methods for the construction of an efficient nano-structured lactate oxidase-SWCNT-biosensor. Biosens Bioelectron. 2015 Feb 15;64:138-46. doi: 10.1016/j.bios.2014.08.072. Epub 2014 Sep 3. PubMed PMID: 25216450; PubMed Central PMCID: PMC4254293.
  6. Morales-Cruz M, Figueroa CM, González-Robles T, Delgado Y, Molina A, Méndez J, Morales M, Griebenow K. Activation of caspase-dependent apoptosis by intracellular delivery of Cytochrome c-based nanoparticles. J Nanobiotechnology. 2014 Sep 2;12:33. doi: 10.1186/s12951-014-0033-9. PubMed PMID: 25179308; PubMed Central PMCID: PMC4237869.
  7. Delgado Y, Morales-Cruz M, Hernández-Román J, Martínez Y, Griebenow K. Chemical glycosylation of cytochrome c improves physical and chemical protein stability. BMC Biochem. 2014 Aug 6;15:16. doi: 10.1186/1471-2091-15-16. PubMed PMID: 25095792; PubMed Central PMCID: PMC4137108.
  8. Méndez J, Morales Cruz M, Delgado Y, Figueroa CM, Orellano EA, Morales M, Monteagudo A, Griebenow K. Delivery of chemically glycosylated cytochrome c immobilized in mesoporous silica nanoparticles induces apoptosis in HeLa cancer cells. Mol Pharm. 2014 Jan 6;11(1):102-11. doi: 10.1021/mp400400j. Epub 2013 Dec 10. PubMed PMID: 24294910; PubMed Central PMCID: PMC3905321.
  9. Flores-Fernández GM, Griebenow K. Glycosylation improves α-chymotrypsin stability upon encapsulation in poly(lactic-co-glycolic)acid microspheres. Results Pharma Sci. 2012;2:46-51. PubMed PMID: 23419866; PubMed Central PMCID: PMC3572538.
  10. Morales-Cruz M, Flores-Fernández GM, Morales-Cruz M, Orellano EA, Rodriguez-Martinez JA, Ruiz M, Griebenow K. Two-step nanoprecipitation for the production of protein-loaded PLGA nanospheres. Results Pharma Sci. 2012;2:79-85. PubMed PMID: 23316451; PubMed Central PMCID: PMC3541529.
  11. Montalvo-Ortiz BL, Sosa B, Griebenow K. Improved enzyme activity and stability in polymer microspheres by encapsulation of protein nanospheres. AAPS PharmSciTech. 2012 Jun;13(2):632-6. doi: 10.1208/s12249-012-9794-3. Epub 2012 Apr 27. PubMed PMID: 22538459; PubMed Central PMCID: PMC3364394.
  12. Méndez J, Monteagudo A, Griebenow K. Stimulus-responsive controlled release system by covalent immobilization of an enzyme into mesoporous silica nanoparticles. Bioconjug Chem. 2012 Apr 18;23(4):698-704. doi: 10.1021/bc200301a. Epub 2012 Mar 13. PubMed PMID: 22375899; PubMed Central PMCID: PMC3329583.
  13. Nicolau E, Méndez J, Fonseca JJ, Griebenow K, Cabrera CR. Bioelectrochemistry of non-covalent immobilized alcohol dehydrogenase on oxidized diamond nanoparticles. Bioelectrochemistry. 2012 Jun;85:1-6. doi: 10.1016/j.bioelechem.2011.11.002. Epub 2011 Nov 20. PubMed PMID: 22154812.

Martín Montoya Zavala, Ph.D.

  1. Joyal JS, Nim S, Zhu T, Sitaras N, Rivera JC, Shao Z, Sapieha P, Hamel D, Sanchez M, Zaniolo K, St-Louis M, Ouellette J, Montoya-Zavala M, Zabeida A, Picard E, Hardy P, Bhosle V, Varma DR, Gobeil F Jr, Beauséjour C, Boileau C, Klein W, Hollenberg M, Ribeiro-da-Silva A, Andelfinger G, Chemtob S. Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis. Nat Med. 2014 Oct;20(10):1165-73. doi: 10.1038/nm.3669. Epub 2014 Sep 14. PubMed PMID: 25216639.

Pasquale Fulvio, Ph.D.

  1. Villa A, Schiavoni M, Chan-Thaw CE, Fulvio PF, Mayes RT, Dai S, More KL, Veith GM, Prati L. Acid-functionalized mesoporous carbon: an efficient support for ruthenium-catalyzed γ-valerolactone production. ChemSusChem. 2015 Aug 10;8(15):2520-8. doi: 10.1002/cssc.201500331. Epub 2015 Jun 18. PubMed PMID: 26089180.
  2. Achtyl JL, Unocic RR, Xu L, Cai Y, Raju M, Zhang W, Sacci RL, Vlassiouk IV, Fulvio PF, Ganesh P, Wesolowski DJ, Dai S, van Duin AC, Neurock M, Geiger FM. Aqueous proton transfer across single-layer graphene. Nat Commun. 2015 Mar 17;6:6539. doi: 10.1038/ncomms7539. PubMed PMID: 25781149; PubMed Central PMCID: PMC4382684.

Walter Silva, Ph.D.

  1. Santiago JM, Torrado AI, Arocho LC, Rosas OR, Rodríguez AE, Toro FK, Salgado IK, Torres YA, Silva WI, Miranda JD. Expression profile of flotillin-2 and its pathophysiological role after spinal cord injury. J Mol Neurosci. 2013 Feb;49(2):347-59. doi: 10.1007/s12031-012-9873-7. Epub 2012 Aug 10. PubMed PMID:22878913; PubMed Central PMCID: PMC3545048.
  2. Salgado IK, Serrano M, García JO, Martínez NA, Maldonado HM, Báez-Pagán CA, Lasalde-Dominicci JA, Silva WI. SorLA in glia: shared subcellular distribution patterns with caveolin-1. Cell Mol Neurobiol. 2012 Apr;32(3):409-21. doi: 10.1007/s10571-011-9771-5. Epub 2011 Nov 30. PubMed PMID: 22127416; PubMed Central PMCID: PMC3753200.